Ascendis observational study for ACH is ready to start

ACHieve is a long-term, multi-center, longitudinal, observational study

in children with achondroplasia. The study was published in Clinicaltrials.gov on the 14th of March 2019. The aim is to study height velocity and comorbidities in children with ACH and is a natural history study, but no study medication will be administered.

Which information will be collected?

1. Annualized height velocity (centimeters/year) in children with achondroplasia [ Time Frame: Up to 5 years ]. Subjects will undergo a series of height measurements (in centimeters) on Day 1 and then every 6 months over the study period with height velocity reported in cm/year

2. Collection of the natural history of achondroplasia symptoms in children with achondroplasia [ Time Frame: Up to 5 years ], to characterize achondroplasia symptoms in children with achondroplasia

 

The company will recruit approximately 200 children with achondroplasia with ages between 0 to 8 years old.

The currently selected locations, not yet recruiting but in preparation, are listed below. The study is heading to start in the next few months.

United States, Arkansas
Little Rock, Arkansas, United States, 72211   Not yet recruiting
 
United States, California
Oakland, California, United States, 94609   Not yet recruiting
 
United States, Delaware
Wilmington, Delaware, United States, 19803   Not yet recruiting
 
United States, Georgia
Atlanta, Georgia, United States, 30322   Not yet recruiting
 
United States, Missouri
Columbia, Missouri, United States, 65212   Not yet recruiting
 
United States, Washington
Seattle, Washington, United States, 98105   Not yet recruiting
 
Australia, Victoria
Parkville, Victoria, Australia, 3052   Not yet recruiting
 
Canada
Montréal, Canada, H3T 1C5   Not yet recruiting
 
Germany
Berlin, Germany, 13353   Not yet recruiting
 
United Kingdom
Liverpool, United Kingdom, LA12 2AP   Not yet recruiting